PDE11A anticorps (C-Term)
Aperçu rapide pour PDE11A anticorps (C-Term) (ABIN2789717)
Antigène
Voir toutes PDE11A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- PDE11A Antibody - C-terminal region
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Séquence
- VTSEFFEQGD RERLELKLTP SAIFDRNRKD ELPRLQLEWI DSICMPLYQA
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against PDE11A. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64064-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PDE11A (phosphodiesterase 11A (PDE11A))
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Autre désignation
- PDE11A
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Sujet
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Background Information: The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia.
Gene Name: Phosphodiesterase 11A
Alternative Symbols: PPNAD2
Protein Name: Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
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Poids moléculaire
- 56kDa
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ID gène
- 50940
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NCBI Accession
- NP_001070664
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UniProt
- Q9HCR9
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Pathways
- cAMP Metabolic Process
Antigène
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