Melatonin Receptor 1B anticorps (N-Term)

N° du produit ABIN2789720

Cet anticorps Lapin Polyclonal détecte spécifiquement Melatonin Receptor 1B dans WB. Il présente une réactivité envers Humain, Porc et Lapin et a été mentionné dans 1 publication.

Aperçu rapide pour Melatonin Receptor 1B anticorps (N-Term) (ABIN2789720)

Antigène: Melatonin Receptor 1B (MTNR1B)

Reactivité: Humain, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Melatonin Receptor 1B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Melatonin Receptor 1B anticorps

Épitope: N-Term

Séquence: SFANCCEAGG WAVRPGWSGA GSARPSRTPR PPWVAPALSA VLIVTTAVDV

Homologie: Human: 100%, Pig: 79%, Rabbit: 79%

Attributs du produit: This is a rabbit polyclonal antibody against MTNR1B. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 362 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Melatonin Receptor 1B (ABIN2789720)

Santoro, Mori, Marani, Grasso, Cambria, Blandino, Muti, Strano: "Blockage of melatonin receptors impairs p53-mediated prevention of DNA damage accumulation." dans: Carcinogenesis, Vol. 34, Issue 5, pp. 1051-61, (2013) (PubMed).

Détails sur Melatonin Receptor 1B

Antigène: Melatonin Receptor 1B (MTNR1B)

Autre désignation: MTNR1B

Sujet: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.
Alias Symbols: FGQTL2, MEL-1B-R, MT2
Protein Interaction Partner: GNAI1, GPR50, ITM2C, HNRNPA0, GNB4, PPM1G, PI4KA, PDIA6, VPS35, IRS4, COPA, CTNND1, MTNR1B, MTNR1A, FLNA, YWHAQ, GNB1, GNAI3, GNAI2, HSPA5, CANX,
Protein Size: 362

Poids moléculaire: 40 kDa

ID gène: 4544

NCBI Accession: NM_005959, NP_005950

UniProt: P49286