Myotilin anticorps (C-Term)
Aperçu rapide pour Myotilin anticorps (C-Term) (ABIN2789737)
Antigène
Voir toutes Myotilin (MYOT) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- MYOT Antibody - C-terminal region
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Séquence
- RNNEMVQFNT DRISLYQDNT GRVTLLIKDV NKKDAGWYTV SAVNEAGVTT
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against MYOT. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64117-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Myotilin (MYOT)
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Autre désignation
- MYOT
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Sujet
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Background Information: This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Gene Name: Myotilin
Alternative Symbols: MFM3, TTID, TTOD, LGMD1, LGMD1A
Protein Name: Myotilin
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Poids moléculaire
- 55kDa
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ID gène
- 9499
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NCBI Accession
- NP_006781
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UniProt
- Q9UBF9
Antigène
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