GCSH anticorps (C-Term)

N° du produit ABIN2789765

L’anticorps anti-GCSH Polyclonal Lapin est utilisé pour la détection de GCSH dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye, Saccharomyces cerevisiae et Poisson zèbre (Danio rerio). Il a été validé pour WB.

Aperçu rapide pour GCSH anticorps (C-Term) (ABIN2789765)

Antigène: GCSH (Glycine Cleavage System H Protein (GCSH))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GCSH est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GCSH anticorps

Épitope: C-Term

Fonction: GCSH Antibody - C-terminal region

Séquence: NEALAENPGL VNKSCYEDGW LIKMTLSNPS ELDELMSEEA YEKYIKSIEE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Yeast: 82%, Zebrafish: 77%

Attributs du produit: This is a rabbit polyclonal antibody against GCSH. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64203-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur GCSH

Antigène: GCSH (Glycine Cleavage System H Protein (GCSH))

Autre désignation: GCSH

Sujet:

Background Information: Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.

Gene Name: Glycine cleavage system protein H (aminomethyl carrier)

Alternative Symbols: GCE, NKH

Protein Name: Glycine cleavage system H protein, mitochondrial

Poids moléculaire: 14kDa

ID gène: 2653

NCBI Accession: NP_004474

UniProt: P23434