JIP3 anticorps (N-Term)
Aperçu rapide pour JIP3 anticorps (N-Term) (ABIN2789770)
Antigène
Voir toutes JIP3 (MAPK8IP3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- QYEREKALRR QAEEKFIEFE DALEQEKKEL QIQVEHYEFQ TRQLELKAKN
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Homologie
- Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%, Yeast: 100%, Zebrafish: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against MAPK8IP3. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 1330 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- JIP3 (MAPK8IP3) (Mitogen-Activated Protein Kinase 8 Interacting Protein 3 (MAPK8IP3))
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Autre désignation
- MAPK8IP3
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Sujet
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The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport.
Alias Symbols: DKFZp762N1113, FLJ00027, JIP3, JSAP1, KIAA1066, SYD2, syd
Protein Interaction Partner: MAP2K3, MAP3K5, BCL6, KAT2A, ALK, KLC2, RIC8A, MAPK8IP3, MAPK8IP2, TLR9, MAPK8IP1, TLR4, TLR2, MAP2K7, MAPK10, MAPK9, MAP2K4, MAPK8, PTK2, ARL4D, CASP3, MAP3K11, KLC1, MAP2K1, RAF1, MAP3K1, SRC,
Protein Size: 1330 -
Poids moléculaire
- 147 kDa
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ID gène
- 23162
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NCBI Accession
- NM_001040439, NP_001035529
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UniProt
- E9PFH7
Antigène
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