SYNGAP1 anticorps (C-Term)

N° du produit ABIN2789829

L’anticorps Lapin Polyclonal anti-SYNGAP1 a été validé pour WB. Il convient pour détecter SYNGAP1 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Cheval, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour SYNGAP1 anticorps (C-Term) (ABIN2789829)

Antigène: SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYNGAP1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SYNGAP1 anticorps

Épitope: C-Term

Séquence: EYKLKEYSKS MDESRLDRVK EYEEEIHSLK ERLHMSNRKL EEYERRLLSQ

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SYNGAP1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1343 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SYNGAP1

Antigène: SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))

Autre désignation: SYNGAP1

Sujet: The protein encoded by this gene is a major component of the postsynaptic density (PSD), a group of proteins found associated with NMDA receptors at synapses. The encoded protein is phosphorylated by calmodulin-dependent protein kinase II and dephosphorylated by NMDA receptor activation. Defects in this gene are a cause of mental retardation autosomal dominant type 5 (MRD5).
Alias Symbols: DKFZp761G1421, KIAA1938, MRD5, RASA1, RASA5, SYNGAP
Protein Interaction Partner: SAAL1, DLGAP4, GRIN1, ULK1, ULK2, MPDZ, CAMK2A, TRIP6, DLG4, GRIN2D, DLG3, KDR, PDGFRB, GRIN2B,
Protein Size: 1343

Poids moléculaire: 148 kDa

ID gène: 8831

NCBI Accession: NM_006772, NP_006763

UniProt: Q96PV0

Pathways: Regulation of long-term Neuronal Synaptic Plasticity