Deoxyguanosine Kinase anticorps (C-Term)

N° du produit ABIN2789830

Détail du produit anti-Deoxyguanosine Kinase anticorps

Antigène: Deoxyguanosine Kinase (DGUOK)

Épitope: C-Term

Reactivité: Humain, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Deoxyguanosine Kinase est non-conjugé

Application: Western Blotting (WB)

Séquence: EQLHGQHEAW LIHKTTKLHF EALMNIPVLV LDVNDDFSEE VTKQEDLMRE

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Pig: 86%, Rabbit: 86%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against DGUOK. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DGUOK

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 277 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Deoxyguanosine Kinase

Antigène: Deoxyguanosine Kinase (DGUOK)

Autre désignation: DGUOK (DGUOK Produits)

Synonymes: anticorps DGUOK, anticorps zgc:86625, anticorps dgk, anticorps DDBDRAFT_0218264, anticorps DDBDRAFT_0233982, anticorps DDB_0218264, anticorps DDB_0233982, anticorps MTDPS3, anticorps dGK, anticorps dGK1, anticorps dGK2, anticorps dGK3, anticorps deoxyguanosine kinase, anticorps deoxyguanosine kinase L homeolog, anticorps DGUOK, anticorps dguok, anticorps dguok.L, anticorps dgk, anticorps Ccan_04750, anticorps Dguok

Sujet: In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.
Alias Symbols: dGK
Protein Interaction Partner: UBC, PXN, LIG4, APP, DGUOK,
Protein Size: 277

Poids moléculaire: 28 kDa

ID gène: 1716

NCBI Accession: NM_080916, NP_550438

UniProt: Q16854

Pathways: Ribonucleoside Biosynthetic Process