Deoxyguanosine Kinase anticorps (C-Term)

N° du produit ABIN2789830

Cet anticorps anti-Deoxyguanosine Kinase Polyclonal Lapin (ABIN2789830) détecte spécifiquement Deoxyguanosine Kinase dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Porc et Lapin.

Aperçu rapide pour Deoxyguanosine Kinase anticorps (C-Term) (ABIN2789830)

Antigène: Deoxyguanosine Kinase (DGUOK)

Reactivité: Humain, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Deoxyguanosine Kinase est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Deoxyguanosine Kinase anticorps

Épitope: C-Term

Fonction: DGUOK Antibody - C-terminal region

Séquence: EQLHGQHEAW LIHKTTKLHF EALMNIPVLV LDVNDDFSEE VTKQEDLMRE

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Pig: 86%, Rabbit: 86%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against DGUOK. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DGUOK

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64409-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Deoxyguanosine Kinase

Antigène: Deoxyguanosine Kinase (DGUOK)

Autre désignation: DGUOK

Sujet:

Background Information: In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.

Alternative Symbols: dGK, NCPH, PEOB4, MTDPS3

Protein Name: Deoxyguanosine kinase, mitochondrial

Poids moléculaire: 28kDa

ID gène: 1716

NCBI Accession: NP_550438

UniProt: Q16854

Pathways: Ribonucleoside Biosynthetic Process