CD51 anticorps (C-Term)

N° du produit ABIN2789883

Détail du produit anti-CD51 anticorps

Antigène: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Chévre, Cobaye, Cheval, Lapin, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD51 est non-conjugé

Application: Western Blotting (WB)

Séquence: PVWVIILAVL AGLLLLAVLV FVMYRMGFFK RVRPPQEEQE REQLQPHENG

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ITGAV. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ITGAV

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1002 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CD51

Antigène: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Autre désignation: ITGAV (ITGAV Produits)

Synonymes: anticorps 1110004F14Rik, anticorps 2610028E01Rik, anticorps CD51, anticorps D430040G12Rik, anticorps MSK8, anticorps VNRA, anticorps VTNR, anticorps Cd51, anticorps integrin subunit alpha V, anticorps integrin alpha V, anticorps ITGAV, anticorps Itgav

Sujet: ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8, 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands, the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants.
Alias Symbols: CD51, DKFZp686A08142, MSK8, VNRA
Protein Interaction Partner: UBC, EPHA2, THBS1, FN1, KRT3, MCAT, FBXO6, BCAR1, PXN, PHKA2, CSF1R, CBL, MMP2, ILK, PLP1, CALR, ANGPTL3, EDIL3, CYR61, PAK4, ITGB8, ADAM9, AUP1, CD47, PTK2, MMP14, P2RY2, L1CAM, AZGP1, TGFB1, THY1, F2R, PDGFRA, ITGB3, SPP1, ITGB5, ITGB6, ITGB1, NID1, ICA
Protein Size: 1002

Poids moléculaire: 100 kDa

ID gène: 3685

NCBI Accession: NM_001144999, NP_001138471

UniProt: E7EWZ6

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex