MMP17 anticorps (C-Term)
Aperçu rapide pour MMP17 anticorps (C-Term) (ABIN2789884)
Antigène
Voir toutes MMP17 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- YPQSTARDWL VCGDSQADGS VAAGVDAAEG PRAPPGQHDQ SRSEDGYEVC
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Homologie
- Cow: 79%, Horse: 93%, Human: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against MMP17. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 603 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))
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Autre désignation
- MMP17
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Sujet
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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.
Alias Symbols: MT4-MMP
Protein Interaction Partner: TNF, MMP2, LRP1,
Protein Size: 603 -
Poids moléculaire
- 66 kDa
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ID gène
- 4326
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NCBI Accession
- NM_016155, NP_057239
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UniProt
- Q9ULZ9
Antigène
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