DMGDH anticorps (Middle Region)

N° du produit ABIN2789895

Détail du produit anti-DMGDH anticorps

Antigène: DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Porc, Cheval, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DMGDH est non-conjugé

Application: Western Blotting (WB)

Séquence: SELHDLRWIE EAAFRGGYDV EIQNITDEFG VLGVAGPYAR RVLQKLTSE

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 83%

Attributs du produit: This is a rabbit polyclonal antibody against Dmgdh. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of mouse DMGDH

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DMGDH

Antigène: DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

Autre désignation: Dmgdh (DMGDH Produits)

Synonymes: anticorps MGC132281, anticorps DMGDHD, anticorps ME2GLYDH, anticorps Me2GlyDH, anticorps 1200014D15Rik, anticorps AI787269, anticorps dimethylglycine dehydrogenase, anticorps dimethylglycine dehydrogenase L homeolog, anticorps D-amino-acid oxidase, anticorps Dimethylglycine dehydrogenase, anticorps glycine cleavage system protein T, anticorps dimethylglycine dehydrogenase precursor, anticorps DMGDH, anticorps dmgdh.L, anticorps dmgdh, anticorps SAR11_1253, anticorps EAMY_RS27375, anticorps EAMY_RS33570, anticorps VDBG_06516, anticorps Sinme_2570, anticorps HALXA_RS03495, anticorps Dmgdh

Sujet: This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.
Alias Symbols: DMGDHD, ME2GLYDH
Protein Size: 869

Poids moléculaire: 93 kDa

ID gène: 29958

NCBI Accession: NM_013391, NP_037523

UniProt: Q9UI17