DMGDH anticorps (Middle Region)

N° du produit ABIN2789895

L’anticorps anti-DMGDH Polyclonal Lapin est utilisé pour la détection de DMGDH dans des échantillons de Humain, Souris, Rat, Porc, Cheval, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien et Cobaye. Il a été validé pour WB.

Aperçu rapide pour DMGDH anticorps (Middle Region) (ABIN2789895)

Antigène: DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

Reactivité: Humain, Souris, Rat, Porc, Cheval, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DMGDH est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DMGDH anticorps

Épitope: Middle Region

Fonction: DMGDH Antibody - middle region

Séquence: SELHDLRWIE EAAFRGGYDV EIQNITDEFG VLGVAGPYAR RVLQKLTSE

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 83%

Attributs du produit: This is a rabbit polyclonal antibody against Dmgdh. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of mouse DMGDH

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64604-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur DMGDH

Antigène: DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

Autre désignation: DMGDH

Sujet:

Background Information: This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.

Gene Name: dimethylglycine dehydrogenase

Alternative Symbols: DMGDHD, ME2GLYDH

Protein Name: dimethylglycine dehydrogenase, mitochondrial

Poids moléculaire: 93kDa

ID gène: 29958

NCBI Accession: NP_037523

UniProt: Q9UI17