PDE8B anticorps (Middle Region)

N° du produit ABIN2789902

Cet anticorps anti-PDE8B Polyclonal Lapin (ABIN2789902) détecte spécifiquement PDE8B dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Cheval, Boeuf (Vache), Chien, Porc, Cobaye, Rat et Poisson zèbre (Danio rerio).

Aperçu rapide pour PDE8B anticorps (Middle Region) (ABIN2789902)

Antigène: PDE8B (phosphodiesterase 8B (PDE8B))

Reactivité: Humain, Souris, Cheval, Boeuf (Vache), Chien, Porc, Cobaye, Rat, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE8B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PDE8B anticorps

Épitope: Middle Region

Fonction: PDE8B Antibody - middle region

Séquence: TELYSPQLGT KDEDPHTSDL VGGLMTDGLR RLSGNEYVFT KNVHQSHSHL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against PDE8B. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64625-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PDE8B

Antigène: PDE8B (phosphodiesterase 8B (PDE8B))

Autre désignation: PDE8B

Sujet:

Background Information: The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.

Gene Name: Phosphodiesterase 8B

Alternative Symbols: ADSD, PPNAD3

Protein Name: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B

Poids moléculaire: 87kDa

ID gène: 8622

NCBI Accession: NP_001025022

UniProt: O95263

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process