PDE8B anticorps (Middle Region)

N° du produit ABIN2789902

Détail du produit anti-PDE8B anticorps

Antigène: PDE8B (phosphodiesterase 8B (PDE8B))

Épitope: Middle Region

Reactivité: Humain, Souris, Cheval, Boeuf (Vache), Chien, Porc, Cobaye, Rat, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE8B est non-conjugé

Application: Western Blotting (WB)

Séquence: TELYSPQLGT KDEDPHTSDL VGGLMTDGLR RLSGNEYVFT KNVHQSHSHL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against PDE8B. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 788 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PDE8B

Antigène: PDE8B (phosphodiesterase 8B (PDE8B))

Autre désignation: PDE8B (PDE8B Produits)

Synonymes: anticorps PDE8B, anticorps ADSD, anticorps PPNAD3, anticorps B230331L10Rik, anticorps C030047E14Rik, anticorps RNPDE8B, anticorps phosphodiesterase 8B, anticorps high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B, anticorps PDE8B, anticorps LOC100468338, anticorps pde8b, anticorps Pde8b

Sujet: The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ADSD, FLJ11212, PPNAD3
Protein Interaction Partner: UBC,
Protein Size: 788

Poids moléculaire: 87 kDa

ID gène: 8622

NCBI Accession: NM_001029851, NP_001025022

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process