TXNRD3 anticorps (Middle Region)
Aperçu rapide pour TXNRD3 anticorps (Middle Region) (ABIN2789949)
Antigène
Voir toutes TXNRD3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- NHISSLNWGY RLSLREKAVA YVNSYGEFVE HHKIKATNKK GQETYYTAAQ
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Homologie
- Dog: 86%, Guinea Pig: 77%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 85%, Rat: 79%, Zebrafish: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against TXNRD3. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 607 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TXNRD3 (Thioredoxin Reductase 3 (TXNRD3))
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Autre désignation
- TXNRD3
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Sujet
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This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein catalyzes the reduction of thioredoxin, and is implicated in the defense against oxidative stress. It contains a selenocysteine (Sec) residue (which is essential for catalytic activity), encoded by a UGA codon, at the penultimate C-terminal position. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: TGR, TR2, TRXR3
Protein Interaction Partner: UBC,
Protein Size: 607 -
Poids moléculaire
- 66 kDa
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ID gène
- 114112
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NCBI Accession
- NM_001173513, NP_001166984
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UniProt
- Q86VQ6
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Pathways
- Cell RedoxHomeostasis
Antigène
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