EIF3I anticorps (C-Term)

N° du produit ABIN2789974

L’anticorps Lapin Polyclonal anti-EIF3I a été validé pour WB, IHC et IP. Il convient pour détecter EIF3I dans des échantillons de Humain, Souris, Rat, Chien, Cheval, Lapin, Boeuf (Vache) et Cobaye.

Aperçu rapide pour EIF3I anticorps (C-Term) (ABIN2789974)

Antigène: EIF3I (Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Lapin, Boeuf (Vache), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF3I est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-EIF3I anticorps

Épitope: C-Term

Séquence: NVKEHSRQIN DIQLSRDMTM FVTASKDNTA KLFDSTTLEH QKTFRTERPV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against EIF3I. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 325 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur EIF3I

Antigène: EIF3I (Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I))

Autre désignation: EIF3I

Sujet: EIF3I is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Alias Symbols: EIF3S2, PRO2242, TRIP-1, TRIP1, eIF3-beta, eIF3-p36
Protein Interaction Partner: HUWE1, UBC, SUMO2, SUMO3, RNF2, rev, EIF3G, HECW2, EIF3B, CDK18, TARDBP, NPM1, ICAM1, CD81, IGSF8, PAN2, EIF3D, VCAM1, ITGA4, METTL18, gag-pol, DDX3X, PAXIP1, LIG4, EIF3L, EIF3K, EIF3M, EIF3H, EIF3F, EIF3C, EIF3A, EIF3E, CUL3, CDK2, YWHAZ, SIRT7, ARRB1, R
Protein Size: 325

Poids moléculaire: 36 kDa

ID gène: 8668

NCBI Accession: NM_003757, NP_003748

UniProt: Q13347

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Ribonucleoprotein Complex Subunit Organization, Synthesis of DNA