ATL1 anticorps (C-Term)
Aperçu rapide pour ATL1 anticorps (C-Term) (ABIN2789990)
Antigène
Voir toutes ATL1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- DQVAAALWDQ GSTNEALYKL YSAAATHRHL YHQAFPTPKS ESTEQSEKKK
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Homologie
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 77%, Pig: 100%, Rabbit: 92%, Rat: 92%
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Attributs du produit
- This is a rabbit polyclonal antibody against SPG3A. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of human ATL1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ATL1 (Atlastin GTPase 1 (ATL1))
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Autre désignation
- SPG3A
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Sujet
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The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: FSP1, GBP3, SPG3, HSN1D, SPG3A, AD-FSP, atlastin1
Protein Size: 475 -
Poids moléculaire
- 52 kDa
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ID gène
- 51062
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NCBI Accession
- NM_001127713, NP_001121185
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UniProt
- Q8WXF7
Antigène
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