TNK1 anticorps (C-Term)

N° du produit ABIN2790058

L’anticorps anti-TNK1 Polyclonal Lapin est utilisé pour la détection de TNK1 dans des échantillons de Humain, Cobaye, Porc, Lapin et Saccharomyces cerevisiae. Il a été validé pour WB.

Aperçu rapide pour TNK1 anticorps (C-Term) (ABIN2790058)

Antigène: TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))

Reactivité: Humain, Cobaye, Porc, Lapin, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNK1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TNK1 anticorps

Épitope: C-Term

Fonction: TNK1 Antibody - C-terminal region

Séquence: EIRQARAVPQ GPPGLPPRPP LSSSSPQPSQ PSRERLPWPK RKPPHNHPMG

Homologie: Guinea Pig: 83%, Human: 100%, Pig: 85%, Rabbit: 77%, Yeast: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TNK1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65151-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur TNK1

Antigène: TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))

Autre désignation: TNK1

Sujet:

Background Information: The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: Tyrosine kinase, non-receptor, 1

Alternative Symbols: KOS1

Protein Name: Non-receptor tyrosine-protein kinase TNK1

Poids moléculaire: 72kDa

ID gène: 8711

NCBI Accession: NP_003976

UniProt: Q13470