BDKRB1 anticorps (C-Term)
Aperçu rapide pour BDKRB1 anticorps (C-Term) (ABIN2790059)
Antigène
Voir toutes BDKRB1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- BDKRB1 Antibody - C-terminal region
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Séquence
- NFFAFTNSSL NPVIYVFVGR LFRTKVWELY KQCTPKSLAP ISSSHRKEIF
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Homologie
- Human: 100%, Rabbit: 77%
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Attributs du produit
- This is a rabbit polyclonal antibody against BDKRB1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65156-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- BDKRB1 (Bradykinin Receptor B1 (BDKRB1))
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Autre désignation
- BDKRB1
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Sujet
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Background Information: Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene.
Gene Name: Bradykinin receptor B1
Alternative Symbols: B1R, BKR1, B1BKR, BKB1R, BRADYB1
Protein Name: B1 bradykinin receptor
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Poids moléculaire
- 40kDa
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ID gène
- 623
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NCBI Accession
- NP_000701
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UniProt
- P46663
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Pathways
- ACE Inhibitor Pathway
Antigène
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