Myomesin 1 anticorps (C-Term)

N° du produit ABIN2790069

Détail du produit anti-Myomesin 1 anticorps

Antigène: Myomesin 1 (MYOM1)

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Myomesin 1 est non-conjugé

Application: Western Blotting (WB)

Séquence: FEAGRTAYFT INGVSTADSG KYGLVVKNKY GSETSDFTVS VFIPEEEARM

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against MYOM1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1589 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Myomesin 1

Antigène: Myomesin 1 (MYOM1)

Autre désignation: MYOM1 (MYOM1 Produits)

Synonymes: anticorps SKELEMIN, anticorps D430047A17Rik, anticorps myomesin 1, anticorps myomesin 1, 185kDa, anticorps MYOM1, anticorps Myom1

Sujet: The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD (myomesin 1) and 165 kD (myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and other myofibrillar proteins contains structural modules with strong homology to either fibronectin type III (motif I) or immunoglobulin C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique N-terminal region followed by 12 modules of motif I or motif II, in the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins share 50 % sequence identity in this repeat-containing region. The head structure formed by these 2 proteins on one end of the titin string extends into the center of the M band. The integrating structure of the sarcomere arises from muscle-specific members of the superfamily of immunoglobulin-like proteins. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: MGC134946, MGC134947, SKELEMIN
Protein Interaction Partner: TTN, MYH9, MYOM1,
Protein Size: 1589

Poids moléculaire: 178 kDa

ID gène: 8736

NCBI Accession: NM_019856, NP_062830

UniProt: P52179