NANS anticorps (C-Term)

N° du produit ABIN2790121

Cet anticorps Lapin Polyclonal détecte spécifiquement NANS dans WB. Il présente une réactivité envers Humain, Rat, Boeuf (Vache), Chien, Lapin et Porc.

Aperçu rapide pour NANS anticorps (C-Term) (ABIN2790121)

Antigène: NANS (N-Acetylneuraminic Acid Synthase (NANS))

Reactivité: Humain, Rat, Boeuf (Vache), Chien, Lapin, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NANS est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NANS anticorps

Épitope: C-Term

Séquence: DMLTVKVGEP KGYPPEDIFN LVGKKVLVTV EEDDTIMEEL VDNHGKKIKS

Homologie: Cow: 86%, Dog: 79%, Human: 100%, Pig: 86%, Rabbit: 79%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against NANS. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 359 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NANS

Antigène: NANS (N-Acetylneuraminic Acid Synthase (NANS))

Autre désignation: NANS

Sujet: This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively, however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.
Alias Symbols: SAS
Protein Interaction Partner: SUMO2, UBC, NEDD8, ATG3, SMEK2, CNDP2, POLE3, DAK, NPEPPS, SLC9A3R1, RPLP2, MVD, PDIA3, GBP2, EIF4E, CKB, ASS1, BAG3, HSP90AB1, HSP90AA1, PCMT1, CRK, RAD23B, DDA1,
Protein Size: 359

Poids moléculaire: 40 kDa

ID gène: 54187

NCBI Accession: NM_018946, NP_061819

UniProt: Q9NR45