RDH8 anticorps (Middle Region)

N° du produit ABIN2790129

Cet anticorps Lapin Polyclonal détecte spécifiquement RDH8 dans WB. Il présente une réactivité envers Humain, Souris, Porc, Lapin, Rat, Boeuf (Vache), Chien, Cobaye et Cheval.

Aperçu rapide pour RDH8 anticorps (Middle Region) (ABIN2790129)

Antigène: RDH8 (Retinol Dehydrogenase 8 (RDH8))

Reactivité: Humain, Souris, Porc, Lapin, Rat, Boeuf (Vache), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RDH8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RDH8 anticorps

Épitope: Middle Region

Séquence: FDTNFFGAVR LVKAVLPGMK RRRQGHIVVI SSVMGLQGVI FNDVYAASKF

Homologie: Cow: 93%, Dog: 92%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RDH8. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human RDH8

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 311 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RDH8

Antigène: RDH8 (Retinol Dehydrogenase 8 (RDH8))

Autre désignation: RDH8

Sujet: All-trans-retinol dehydrogenase (RDH8) is a visual cycle enzyme that reduces all-trans-retinal to all-trans-retinol in the presence of NADPH (Rattner et al., 2000 [PubMed 10753906]). It is a member of the short chain dehydrogenase/reductase family and is located in the outer segments of photoreceptors, hence it is also known as photoreceptor retinol dehydrogenase. It is important in the visual cycle by beginning the rhodopsin regeneration pathway by reducing all-trans-retinal, the product of bleached and hydrolysed rhodopsin.
Alias Symbols: PRRDH, SDR28C2
Protein Size: 311

Poids moléculaire: 34 kDa

ID gène: 50700

NCBI Accession: NM_015725, NP_056540

UniProt: Q9NYR8