SELPLG anticorps (C-Term)

N° du produit ABIN2790195

Détail du produit anti-SELPLG anticorps

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Épitope: C-Term

Reactivité: Humain, Rat, Boeuf (Vache), Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SELPLG est non-conjugé

Application: Western Blotting (WB)

Séquence: EMVCISSLLP DGGEGPSATA NGGLSKAKSP GLTPEPREDR EGDDLTLHSF

Homologie: Cow: 91%, Dog: 83%, Guinea Pig: 92%, Human: 100%, Rat: 83%

Attributs du produit: This is a rabbit polyclonal antibody against SELPLG. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SELPLG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 412 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SELPLG

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Autre désignation: SELPLG (SELPLG Produits)

Synonymes: anticorps CD162, anticorps CLA, anticorps PSGL-1, anticorps PSGL1, anticorps SELPLG, anticorps SELPG, anticorps Psgl-1, anticorps Psgl1, anticorps Selp1, anticorps Selpl, anticorps selectin P ligand, anticorps selectin, platelet (p-selectin) ligand, anticorps clasper, anticorps SELPLG, anticorps Selplg, anticorps cla

Sujet: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.
Alias Symbols: CD162, CLA, PSGL-1, PSGL1
Protein Interaction Partner: MAGEA1, TNIP1, PIK3R1, GALNT4, BACE1, TPST2, TPST1, SELL, SYK, MSN, SELP, SELE, VCAN, CTSG, SELPLG,
Protein Size: 412

Poids moléculaire: 39 kDa

ID gène: 6404

NCBI Accession: NM_003006, NP_002997

UniProt: Q14242