SELPLG anticorps (C-Term)

N° du produit ABIN2790195

Cet anticorps Lapin Polyclonal détecte spécifiquement SELPLG dans WB. Il présente une réactivité avec des échantillons de Humain, Rat, Boeuf (Vache), Chien et Cobaye.

Aperçu rapide pour SELPLG anticorps (C-Term) (ABIN2790195)

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Reactivité: Humain, Rat, Boeuf (Vache), Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SELPLG est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SELPLG anticorps

Épitope: C-Term

Fonction: SELPLG Antibody - C-terminal region

Séquence: EMVCISSLLP DGGEGPSATA NGGLSKAKSP GLTPEPREDR EGDDLTLHSF

Homologie: Cow: 91%, Dog: 83%, Guinea Pig: 92%, Human: 100%, Rat: 83%

Attributs du produit: This is a rabbit polyclonal antibody against SELPLG. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SELPLG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65609-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur SELPLG

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Autre désignation: SELPLG

Sujet:

Background Information: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.

Gene Name: Selectin P ligand

Alternative Symbols: CLA, CD162, PSGL1, PSGL-1

Protein Name: P-selectin glycoprotein ligand 1

Poids moléculaire: 39kDa

ID gène: 6404

NCBI Accession: NP_002997

UniProt: Q14242