SPAG1 anticorps (C-Term)

N° du produit ABIN2790232

Cet anticorps Lapin Polyclonal détecte spécifiquement SPAG1 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour SPAG1 anticorps (C-Term) (ABIN2790232)

Antigène: SPAG1 (Sperm Associated Antigen 1 (SPAG1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPAG1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SPAG1 anticorps

Épitope: C-Term

Séquence: KIEIQEVNEG KEEPGRPAGE VSMGCLASEK GGKSSRSPED PEKLPIAKPN

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SPAG1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SPAG1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 926 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SPAG1

Antigène: SPAG1 (Sperm Associated Antigen 1 (SPAG1))

Autre désignation: SPAG1

Sujet: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization.
Alias Symbols: FLJ32920, HSD-3.8, SP75, TPIS
Protein Interaction Partner: UBC, GNB1, PCNA, PRKCA, DYT10,
Protein Size: 926

Poids moléculaire: 104 kDa

ID gène: 6674

NCBI Accession: NM_003114, NP_003105

UniProt: Q07617