SPAG1 anticorps (C-Term)
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- Antigène Voir toutes SPAG1 Anticorps
- SPAG1 (Sperm Associated Antigen 1 (SPAG1))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SPAG1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- KIEIQEVNEG KEEPGRPAGE VSMGCLASEK GGKSSRSPED PEKLPIAKPN
- Homologie
- Human: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against SPAG1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human SPAG1
- Top Product
- Discover our top product SPAG1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 926 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- SPAG1 (Sperm Associated Antigen 1 (SPAG1))
- Autre désignation
- SPAG1 (SPAG1 Produits)
- Synonymes
- anticorps cb1089, anticorps MGC162178, anticorps wu:fj78g10, anticorps sp75, anticorps tpis, anticorps hsd-3.8, anticorps HSD-3.8, anticorps SP75, anticorps TPIS, anticorps sperm associated antigen 1, anticorps sperm associated antigen 1a, anticorps SPAG1, anticorps spag1a, anticorps CpipJ_CPIJ006297, anticorps spag1, anticorps Spag1
- Sujet
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The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization.
Alias Symbols: FLJ32920, HSD-3.8, SP75, TPIS
Protein Interaction Partner: UBC, GNB1, PCNA, PRKCA, DYT10,
Protein Size: 926 - Poids moléculaire
- 104 kDa
- ID gène
- 6674
- NCBI Accession
- NM_003114, NP_003105
- UniProt
- Q07617
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