SPG21 anticorps (C-Term)

N° du produit ABIN2790233

Détail du produit anti-SPG21 anticorps

Antigène: SPG21 (Spastic Paraplegia 21 (SPG21))

Épitope: C-Term

Reactivité: Humain, Boeuf (Vache), Souris, Lapin, Rat, Mouton, Chien, Cobaye, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPG21 est non-conjugé

Application: Western Blotting (WB)

Séquence: LCRSAEVNLY VQIHLLQFHG TKYAAIDPSM VSAEELEVQK GSLGISQEEQ

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 79%, Rat: 86%, Sheep: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SPG21. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SPG21

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 308 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SPG21

Antigène: SPG21 (Spastic Paraplegia 21 (SPG21))

Autre désignation: SPG21 (SPG21 Produits)

Synonymes: anticorps ACP33, anticorps GL010, anticorps MAST, anticorps BM-019, anticorps C78576, anticorps D9Wsu18e, anticorps Maspardin, anticorps wu:fd07h02, anticorps zgc:73091, anticorps SPG21, maspardin, anticorps spastic paraplegia 21 (autosomal recessive, Mast syndrome), anticorps SPG21, maspardin S homeolog, anticorps SPG21, anticorps Spg21, anticorps spg21.S, anticorps spg21

Sujet: The protein encoded by this gene was identified by a two-hybrid screen using CD4 as the bait. It binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. At least three different transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: ACP33, BM-019, GL010, MASPARDIN, MAST
Protein Interaction Partner: INCA1, SPRED2, DTX3L, CMTM5, TRIM9, DTX2, REEP6, FAM114A1, ATPAF2, EFHC2, CCDC33, CCDC102B, TRIM54, AGTRAP, CTPS2, S100B, PRPS1, KRT15, CRYAA, TRIM23, CUTC, ARL6IP1, IKZF3, MID2, RABAC1, TFG, TRAF2, TRAF1, TCF12, TCF4, UBC, GSK3A, DHX40, YLPM1, HMGCS1, AK
Protein Size: 308

Poids moléculaire: 35 kDa

ID gène: 51324

NCBI Accession: NM_016630, NP_057714

UniProt: Q9NZD8