SPG21 anticorps (C-Term)

N° du produit ABIN2790233

L’anticorps anti-SPG21 Polyclonal Lapin est utilisé pour la détection de SPG21 dans des échantillons de Humain, Boeuf (Vache), Chien, Cobaye, Cheval, Souris, Lapin, Rat, Mouton et Porc. Il a été validé pour WB.

Aperçu rapide pour SPG21 anticorps (C-Term) (ABIN2790233)

Antigène: SPG21 (Spastic Paraplegia 21 (SPG21))

Reactivité: Humain, Boeuf (Vache), Chien, Cobaye, Cheval, Souris, Lapin, Rat, Mouton, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPG21 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SPG21 anticorps

Épitope: C-Term

Fonction: SPG21 Antibody - C-terminal region

Séquence: LCRSAEVNLY VQIHLLQFHG TKYAAIDPSM VSAEELEVQK GSLGISQEEQ

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 79%, Rat: 86%, Sheep: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SPG21. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SPG21

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65713-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur SPG21

Antigène: SPG21 (Spastic Paraplegia 21 (SPG21))

Autre désignation: SPG21

Sujet:

Background Information: The protein encoded by this gene was identified by a two-hybrid screen using CD4 as the bait. It binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. At least three different transcript variants encoding two different isoforms have been found for this gene.

Gene Name: Spastic paraplegia 21 (autosomal recessive, Mast syndrome)

Alternative Symbols: MAST, ACP33, GL010, ABHD21, BM-019

Protein Name: Maspardin

Poids moléculaire: 35kDa

ID gène: 51324

NCBI Accession: NP_057714

UniProt: Q9NZD8