Importin 8 anticorps (C-Term)

N° du produit ABIN2790260

Cet anticorps Lapin Polyclonal détecte spécifiquement Importin 8 dans WB. Il présente une réactivité avec des échantillons de Humain, Rat, Chien, Cheval et Cobaye.

Aperçu rapide pour Importin 8 anticorps (C-Term) (ABIN2790260)

Antigène: Importin 8 (IPO8)

Reactivité: Humain, Rat, Chien, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Importin 8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Importin 8 anticorps

Épitope: C-Term

Fonction: IPO8 Antibody - C-terminal region

Séquence: PPAVDAVVGQ IVPSILFLFL GLKQVCATRQ LVNREDRSKA EKADMEENEE

Homologie: Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against IPO8. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human IPO8

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65771-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Importin 8

Antigène: Importin 8 (IPO8)

Autre désignation: IPO8

Sujet:

Background Information: The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: Importin 8

Alternative Symbols: RANBP8

Protein Name: Importin-8

Poids moléculaire: 96kDa

ID gène: 10526

NCBI Accession: NP_001177924

UniProt: O15397