Latrophilin 1 anticorps (C-Term)
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- Antigène Voir toutes Latrophilin 1 (LPHN1) Anticorps
- Latrophilin 1 (LPHN1)
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Épitope
- C-Term
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Reactivité
- Rat, Humain, Souris, Boeuf (Vache), Chien, Cobaye, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Latrophilin 1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- YSLRSGDFPP GDGGPEPPRG RNLADAAAFE KMIISELVHN NLRGSSSAAK
- Homologie
- Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against LPHN1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human LPHN1
- Top Product
- Discover our top product LPHN1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 839 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- Latrophilin 1 (LPHN1)
- Autre désignation
- LPHN1 (LPHN1 Produits)
- Synonymes
- anticorps LPHN1, anticorps CIRL1, anticorps CL1, anticorps LEC2, anticorps 2900070I05Rik, anticorps AI182398, anticorps CLIBA, anticorps Lec2, anticorps mKIAA0821, anticorps CL1BA, anticorps adhesion G protein-coupled receptor L1, anticorps ADGRL1, anticorps Adgrl1
- Sujet
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This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane.
Alias Symbols: CIRL1, CL1, LEC2
Protein Interaction Partner: PSMA3, ELAVL1, UBC, CACNA1A, APC, ANKS1A, SHANK1, SHANK2, DLG4, DLG3, ROS1,
Protein Size: 839 - Poids moléculaire
- 95 kDa
- ID gène
- 22859
- NCBI Accession
- NM_001008701
- UniProt
- O94910
- Pathways
- Synaptic Membrane, Synaptic Vesicle Exocytosis
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