STXBP4 anticorps (N-Term)

N° du produit ABIN2790280

Détail du produit anti-STXBP4 anticorps

Antigène: STXBP4 (Syntaxin Binding Protein 4 (STXBP4))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STXBP4 est non-conjugé

Application: Western Blotting (WB)

Séquence: SVNKESMIGV SFEEAKSIIT GAKLRLESAW EIAFIRQKSD NIQPENLSCT

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against STXBP4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human STXBP4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 553 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur STXBP4

Antigène: STXBP4 (Syntaxin Binding Protein 4 (STXBP4))

Autre désignation: STXBP4 (STXBP4 Produits)

Synonymes: anticorps STXBP4, anticorps LOC733742, anticorps MGC131203, anticorps DKFZp468L076, anticorps Synip, anticorps 6030470M02Rik, anticorps syntaxin binding protein 4, anticorps syntaxin binding protein 4 L homeolog, anticorps STXBP4, anticorps stxbp4, anticorps stxbp4.L, anticorps Stxbp4

Sujet: STXBP4 plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. STXBP4 inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. STXBP4 may also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.
Alias Symbols: FLJ16496, MGC149829, MGC50337, Synip
Protein Interaction Partner: KLHL42, LATS2, ATN1, UBC, Plk1, STX4,
Protein Size: 553

Poids moléculaire: 62 kDa

ID gène: 252983

NCBI Accession: NM_178509, NP_848604

UniProt: Q6ZWJ1