STXBP4 anticorps (N-Term)
Aperçu rapide pour STXBP4 anticorps (N-Term) (ABIN2790280)
Antigène
Voir toutes STXBP4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- STXBP4 Antibody - N-terminal region
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Séquence
- SVNKESMIGV SFEEAKSIIT GAKLRLESAW EIAFIRQKSD NIQPENLSCT
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Homologie
- Human: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against STXBP4. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human STXBP4
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65839-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- STXBP4 (Syntaxin Binding Protein 4 (STXBP4))
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Autre désignation
- STXBP4
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Sujet
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Background Information: STXBP4 plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. STXBP4 inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. STXBP4 may also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.
Gene Name: Syntaxin binding protein 4
Alternative Symbols: Synip
Protein Name: Syntaxin-binding protein 4
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Poids moléculaire
- 62kDa
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ID gène
- 252983
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NCBI Accession
- NP_848604
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UniProt
- Q6ZWJ1
Antigène
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