CHMP5 anticorps (C-Term)

N° du produit ABIN2790285

Détail du produit anti-CHMP5 anticorps

Antigène: CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Chien, Poisson zèbre (Danio rerio), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHMP5 est non-conjugé

Application: Western Blotting (WB)

Séquence: LDALGDELLA DEDSSYLDEA ASAPAIPEGV PTDTKNKDGV LVDEFGLPQI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 80%

Attributs du produit: This is a rabbit polyclonal antibody against Chmp5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Chmp5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 219 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CHMP5

Antigène: CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))

Autre désignation: Chmp5 (CHMP5 Produits)

Synonymes: anticorps SNF7DC2, anticorps cgi-34, anticorps hspc177, anticorps pnas-2, anticorps vps60, anticorps chmp5, anticorps zgc:64125, anticorps C9orf83, anticorps HSPC177, anticorps PNAS-2, anticorps Vps60, anticorps 2210412K09Rik, anticorps AW545668, anticorps RGD1305968, anticorps charged multivesicular body protein 5 S homeolog, anticorps charged multivesicular body protein 5b, anticorps charged multivesicular body protein 5, anticorps charged multivesicular body protein 5 L homeolog, anticorps chromatin modifying protein 5, anticorps chmp5.S, anticorps chmp5b, anticorps CHMP5, anticorps chmp5.L, anticorps chmp5, anticorps Chmp5

Sujet: Chmp5 is a probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis. ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4.
Alias Symbols: 2210412K09Rik, AW545668
Protein Interaction Partner: Ndn,
Protein Size: 219

Poids moléculaire: 24 kDa

ID gène: 76959

NCBI Accession: NM_029814, NP_084090

UniProt: Q9D7S9