CHRDL2 anticorps (N-Term)

N° du produit ABIN2790324

Détail du produit anti-CHRDL2 anticorps

Antigène: CHRDL2 (Chordin-Like 2 (CHRDL2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHRDL2 est non-conjugé

Application: Western Blotting (WB)

Séquence: CTEGQIYCGL TTCPEPGCPA PLPLPDSCCQ ACKDEASEQS DEEDSVQSLH

Homologie: Human: 100%, Mouse: 83%, Rat: 75%, Yeast: 90%

Attributs du produit: This is a rabbit polyclonal antibody against CHRDL2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CHRDL2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 451 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CHRDL2

Antigène: CHRDL2 (Chordin-Like 2 (CHRDL2))

Autre désignation: CHRDL2 (CHRDL2 Produits)

Synonymes: anticorps BNF1, anticorps CHL2, anticorps FKSG37, anticorps 1810022C01Rik, anticorps Chl2, anticorps chl, anticorps si:dkey-11j5.7, anticorps si:dkey-11j5.7-like, anticorps chordin like 2, anticorps chordin-like 2, anticorps CHRDL2, anticorps Chrdl2, anticorps chrdl2

Sujet: CHRDL2 is implicated in tumor angiogenesis. CHRDL2 may inhibits BMPs activity by blocking their interaction with their receptors. CHRDL2 has a negative regulator effect on the cartilage formation/regeneration from immature mesenchymal cells, by preventing or reducing the rate of matrix accumulation. CHRDL2 may play a role during myoblast and osteoblast differentiation, and maturation.
Alias Symbols: BNF1, CHL2, DKFZp586N2124, FKSG37
Protein Interaction Partner: GDF5, INHBA, BMP7, BMP6, BMP5, BMP4, BMP2,
Protein Size: 451

Poids moléculaire: 3 kDa

ID gène: 25884

NCBI Accession: NM_015424, NP_056239

UniProt: Q6WN34