SNX15 anticorps (N-Term)

N° du produit ABIN2790379

L’anticorps anti-SNX15 Polyclonal Lapin est utilisé pour la détection de SNX15 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Chévre, Cheval, Cobaye et Porc. Il a été validé pour WB.

Aperçu rapide pour SNX15 anticorps (N-Term) (ABIN2790379)

Antigène: SNX15 (Sorting Nexin 15 (SNX15))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Chévre, Cheval, Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNX15 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SNX15 anticorps

Épitope: N-Term

Fonction: SNX15 Antibody - N-terminal region

Séquence: RKLHGDLAYT HRNLFRRLEE FPAFPRAQVF GRFEASVIEE RRKGAEDLLR

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SNX15. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SNX15

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP66279-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur SNX15

Antigène: SNX15 (Sorting Nexin 15 (SNX15))

Autre désignation: SNX15

Sujet:

Background Information: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.

Alternative Symbols: HSAF001435

Protein Name: Sorting nexin-15 Ensembl ENSP00000316410 EMBL ADP91255.1

Poids moléculaire: 29kDa

ID gène: 29907

NCBI Accession: NP_680086

UniProt: E5KQS6