D2HGDH anticorps (C-Term)

N° du produit ABIN2790469

Détail du produit anti-D2HGDH anticorps

Antigène: D2HGDH (D-2-Hydroxyglutarate Dehydrogenase (D2HGDH))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Lapin, Chien, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp D2HGDH est non-conjugé

Application: Western Blotting (WB)

Séquence: QESPFYVLIE TSGSNAGHDA EKLGHFLEHA LGSGLVTDGT MATDQRKVKM

Homologie: Dog: 79%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 77%, Rabbit: 100%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against D2HGDH. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human D2HGDH

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 521 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur D2HGDH

Antigène: D2HGDH (D-2-Hydroxyglutarate Dehydrogenase (D2HGDH))

Autre désignation: D2HGDH (D2HGDH Produits)

Sujet: This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.
Alias Symbols: D2HGD, FLJ42195, MGC25181
Protein Interaction Partner: SUMO1, UBC,
Protein Size: 521

Poids moléculaire: 55 kDa

ID gène: 728294

NCBI Accession: NM_152783, NP_689996

UniProt: Q8N465