D2HGDH anticorps (N-Term)

N° du produit ABIN2790470

Cet anticorps Lapin Polyclonal détecte spécifiquement D2HGDH dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Poisson zèbre (Danio rerio), Lapin, Chien, Cheval, Boeuf (Vache) et Cobaye.

Aperçu rapide pour D2HGDH anticorps (N-Term) (ABIN2790470)

Antigène: D2HGDH (D-2-Hydroxyglutarate Dehydrogenase (D2HGDH))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Lapin, Chien, Cheval, Boeuf (Vache), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp D2HGDH est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-D2HGDH anticorps

Épitope: N-Term

Fonction: D2HGDH Antibody - N-terminal region

Séquence: AFERIVPGGV VTDPEALQAP NVDWLRTLRG CSKVLLRPRT SEEVSHILRH

Homologie: Cow: 79%, Dog: 92%, Guinea Pig: 85%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 92%, Rat: 93%, Zebrafish: 77%

Attributs du produit: This is a rabbit polyclonal antibody against D2HGDH. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of human D2HGDH

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP66552-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur D2HGDH

Antigène: D2HGDH (D-2-Hydroxyglutarate Dehydrogenase (D2HGDH))

Autre désignation: D2HGDH

Sujet:

Background Information: This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.

Gene Name: D-2-hydroxyglutarate dehydrogenase

Alternative Symbols: D2HGD

Protein Name: D-2-hydroxyglutarate dehydrogenase, mitochondrial

Poids moléculaire: 35kDa

ID gène: 728294

NCBI Accession: NP_001274178

UniProt: Q8N465