IDH3B anticorps (N-Term)

N° du produit ABIN2790475

Détail du produit anti-IDH3B anticorps

Antigène: IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IDH3B est non-conjugé

Application: Western Blotting (WB)

Séquence: SEVQNMASEE KLEQVLSSMK ENKVAIIGKI HTPMEYKGEL ASYDMRLRRK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against IDH3B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human IDH3B

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 385 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur IDH3B

Antigène: IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))

Autre désignation: IDH3B (IDH3B Produits)

Synonymes: anticorps H-IDHB, anticorps RP46, anticorps C78231, anticorps zgc:86647, anticorps MGC79028, anticorps IDH1, anticorps IDH3, anticorps isocitrate dehydrogenase 3 (NAD(+)) beta, anticorps isocitrate dehydrogenase 3 (NAD+) beta, anticorps isocitrate dehydrogenase 3 (NAD+) beta S homeolog, anticorps IDH3B, anticorps Idh3B, anticorps Idh3b, anticorps idh3b, anticorps idh3b.S

Sujet: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.
Alias Symbols: FLJ11043, H-IDHB, MGC903, RP46
Protein Interaction Partner: TP53, SUMO2, ADRB2, MMS19, ATXN2, UBC, EBNA-LP, MAPK6, MYC, RAB35, PRMT1, IDH3A, IDH3G,
Protein Size: 385

Poids moléculaire: 42 kDa

ID gène: 3420

NCBI Accession: NM_006899, NP_008830

UniProt: O43837