POF1B anticorps (N-Term)

N° du produit ABIN2790494

L’anticorps Lapin Polyclonal anti-POF1B a été validé pour WB. Il convient pour détecter POF1B dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Porc et Chien.

Aperçu rapide pour POF1B anticorps (N-Term) (ABIN2790494)

Antigène: POF1B (Premature Ovarian Failure, 1B (POF1B))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Porc, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POF1B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-POF1B anticorps

Épitope: N-Term

Séquence: HYHCYHQSSQ AQQPPEKNVV YERVRTYSGP MNKVVQALDP FNSREVLSPL

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against POF1B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human POF1B

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 589 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur POF1B

Antigène: POF1B (Premature Ovarian Failure, 1B (POF1B))

Autre désignation: POF1B

Sujet: Premature ovarian failure (POF) is characterized by primary or secondary amenorrhea in women less than 40 years old. Two POF susceptibility regions called "POF1" and "POF2" have been identified by breakpoint mapping of X-autosome translocations. POF1 extends from Xq21-qter while POF2 extends from Xq13.3 to Xq21.1. This gene, POF1B, resides in the POF2 region. This gene is expressed at trace levels in mouse prenatal ovary and is barely detectable or absent from adult ovary, in human and in the mouse respectively. This gene's expression is restricted to epithelia with its highest expression in the epidermis, and oro-pharyngeal and gastro-intestinal tracts. The protein encoded by this gene binds non-muscle actin filaments. The role this gene may play in the etiology of premature ovarian failure remains to be determined.
Alias Symbols: FLJ22792, POF, POF2B
Protein Interaction Partner: ESR1, COPS5, UBC, Cdk1, Akap12, Fam134a, Lyplal1, Tpr, UCHL5,
Protein Size: 589

Poids moléculaire: 65 kDa

ID gène: 79983

NCBI Accession: NM_024921, NP_079197

UniProt: Q8WVV4