DAND5 anticorps (N-Term)

N° du produit ABIN2790535

Cet anticorps anti-DAND5 Polyclonal Lapin (ABIN2790535) détecte spécifiquement DAND5 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour DAND5 anticorps (N-Term) (ABIN2790535)

Antigène: DAND5 (DAN Domain Family, Member 5 (DAND5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DAND5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DAND5 anticorps

Épitope: N-Term

Fonction: DAND5 Antibody - N-terminal region

Séquence: SGALPTGSGR PEPQSPRPQS WAAANQTWAL GPGALPPLVP ASALGSWKAF

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against DAND5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human DAND5

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP66786-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur DAND5

Antigène: DAND5 (DAN Domain Family, Member 5 (DAND5))

Autre désignation: DAND5

Sujet:

Background Information: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.

Alternative Symbols: SP1, CER2, COCO, CRL2, CERL2, DANTE, GREM3, CKTSF1B3

Protein Name: DAN domain family member 5

Poids moléculaire: 21kDa

ID gène: 199699

NCBI Accession: NP_689867

UniProt: Q8N907