IYD anticorps (N-Term)

N° du produit ABIN2790550

Cet anticorps anti-IYD Polyclonal Lapin (ABIN2790550) détecte spécifiquement IYD dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Boeuf (Vache), Chien et Lapin.

Aperçu rapide pour IYD anticorps (N-Term) (ABIN2790550)

Antigène: IYD (Iodotyrosine Deiodinase (IYD))

Reactivité: Humain, Rat, Boeuf (Vache), Chien, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IYD est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IYD anticorps

Épitope: N-Term

Fonction: IYD Antibody - N-terminal region

Séquence: NADRSMEKKK GEPRTRAEAR PWVDEDLKDS SDLHQAEEDA DEWQESEENV

Homologie: Cow: 77%, Dog: 79%, Human: 100%, Rabbit: 79%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against IYD. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human IYD

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP66837-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur IYD

Antigène: IYD (Iodotyrosine Deiodinase (IYD))

Autre désignation: IYD

Sujet:

Background Information: This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4.

Alternative Symbols: TDH4, IYD-1, DEHAL1, C6orf71

Protein Name: Iodotyrosine dehalogenase 1

Poids moléculaire: 27kDa

ID gène: 389434

NCBI Accession: NP_001158167

UniProt: Q6PHW0

Pathways: Thyroid Hormone Synthesis