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ATXN7L3 anticorps (Middle Region)

ATXN7L3 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2790607
  • Antigène Voir toutes ATXN7L3 Anticorps
    ATXN7L3 (Ataxin 7-Like 3 (ATXN7L3))
    Épitope
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 18
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)
    Hôte
    • 18
    Lapin
    Clonalité
    • 18
    Polyclonal
    Conjugué
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ATXN7L3 est non-conjugé
    Application
    • 7
    • 7
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    MNKSESDQED NDDINDNDWS YGSEKKAKKR KSDKLWYLPF QNPNSPRRSK
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    Attributs du produit
    This is a rabbit polyclonal antibody against ATXN7L3. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of Human ATXN7L3
    Top Product
    Discover our top product ATXN7L3 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 354 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    ATXN7L3 (Ataxin 7-Like 3 (ATXN7L3))
    Autre désignation
    ATXN7L3 (ATXN7L3 Produits)
    Synonymes
    anticorps E030022H21Rik, anticorps si:busm1-180g5.4, anticorps si:dz180g5.4, anticorps wu:fj12f07, anticorps zgc:136438, anticorps zgc:158566, anticorps ataxin 7 like 3, anticorps ataxin 7-like 3, anticorps ATXN7L3, anticorps Atxn7l3, anticorps atxn7l3
    Sujet
    ATXN7L3 is a component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, ATXN7L3 participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.
    Alias Symbols: DKFZp761G2113
    Protein Interaction Partner: SIRT1, USP22, SECISBP2, SERTAD1, PICK1, USP6, UCHL3, HIST2H2BE, HIST2H2AC, ATXN7, KAT2A, ENY2, TAF5L, SUPT3H, TRRAP, TAF10,
    Protein Size: 354
    Poids moléculaire
    38 kDa
    ID gène
    56970
    NCBI Accession
    NM_020218, NP_064603
    UniProt
    Q14CW9
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