ALG10B anticorps (Middle Region)
Aperçu rapide pour ALG10B anticorps (Middle Region) (ABIN2790719)
Antigène
Voir toutes ALG10B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- ALG10B Antibody - middle region
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Séquence
- GFCGFMFRQT NIIWAVFCAG NVIAQKLTEA WKTELQKKED RLPPIKGPFA
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Homologie
- Dog: 87%, Horse: 80%, Human: 100%, Pig: 87%, Rat: 80%
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Attributs du produit
- This is a rabbit polyclonal antibody against ALG10B. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of Human ALG10B
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP67353-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- ALG10B (Asparagine-Linked Glycosylation 10, alpha-1,2-Glucosyltransferase Homolog B (ALG10B))
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Autre désignation
- ALG10B
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Sujet
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Background Information: ALG10B is a putative alpha-1,2-glucosyltransferase, which adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. ALG10B transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc2Man9GlcNAc(2)-PP-Dol. When coupled to KCNH2 may reduce KCNH2 sensitivity to classic proarrhythmic drug blockade, possibly by mediating glycosylation of KCNH2.
Alternative Symbols: KCR1, ALG10
Protein Name: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase
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Poids moléculaire
- 55kDa
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ID gène
- 144245
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NCBI Accession
- NP_001013642
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UniProt
- Q5I7T1
Antigène
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