CCDC99 anticorps (C-Term)

N° du produit ABIN2790740

Cet anticorps anti-CCDC99 est un anticorps Lapin Polyclonal détectant CCDC99 dans WB. Adapté pour Humain, Rat, Boeuf (Vache), Chien, Cheval, Porc et Lapin.

Aperçu rapide pour CCDC99 anticorps (C-Term) (ABIN2790740)

Antigène: CCDC99 (Coiled-Coil Domain Containing 99 (CCDC99))

Reactivité: Humain, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCDC99 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CCDC99 anticorps

Épitope: C-Term

Séquence: PRLAAESKLQ TEVKEGKETS SKLEKETCKK LHPILYVSSK STPETQCPQQ

Homologie: Cow: 79%, Dog: 93%, Horse: 92%, Human: 100%, Pig: 93%, Rabbit: 86%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against CCDC99. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CCDC99

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 605 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CCDC99

Antigène: CCDC99 (Coiled-Coil Domain Containing 99 (CCDC99))

Autre désignation: CCDC99

Sujet: CCDC99 is required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. CCDC99 is also required for correct spindle orientation. It does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment.
Alias Symbols: FLJ20364, FLJ40690, CCDC99
Protein Interaction Partner: RTP5, PPP1R18, DYX1C1, SPDL1, USP15, TRAF4, CA8, NEK9, SIRT1, HMGCS1, DHX40, YLPM1, SF3B3, ITSN1, UBC, KIAA1377, GPS2,
Protein Size: 605

Poids moléculaire: 67 kDa

ID gène: 54908

NCBI Accession: NM_017785, NP_060255

UniProt: Q96EA4