CCDC99 anticorps (C-Term)

N° du produit ABIN2790740

Détail du produit anti-CCDC99 anticorps

Antigène: CCDC99 (Coiled-Coil Domain Containing 99 (CCDC99))

Épitope: C-Term

Reactivité: Humain, Rat, Lapin, Boeuf (Vache), Chien, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCDC99 est non-conjugé

Application: Western Blotting (WB)

Séquence: PRLAAESKLQ TEVKEGKETS SKLEKETCKK LHPILYVSSK STPETQCPQQ

Homologie: Cow: 79%, Dog: 93%, Horse: 92%, Human: 100%, Pig: 93%, Rabbit: 86%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against CCDC99. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CCDC99

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 605 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CCDC99

Antigène: CCDC99 (Coiled-Coil Domain Containing 99 (CCDC99))

Autre désignation: CCDC99 (CCDC99 Produits)

Synonymes: anticorps CCDC99, anticorps CG15415, anticorps Dmel\\CG15415, anticorps SPINDLY, anticorps ccdc99, anticorps 1700018I02Rik, anticorps 2600001J17Rik, anticorps 2810049B11Rik, anticorps AA409762, anticorps Ccdc99, anticorps RGD1306908, anticorps ccdc99-a, anticorps ccdc99-b, anticorps spdl1-a, anticorps spdl1-b, anticorps spdl1, anticorps spindle apparatus coiled-coil protein 1, anticorps CG15415 gene product from transcript CG15415-RB, anticorps Tetratricopeptide repeat (TPR)-like superfamily protein, anticorps spindle apparatus coiled-coil protein 1 L homeolog, anticorps spindle apparatus coiled-coil protein 1 S homeolog, anticorps SPDL1, anticorps Spindly, anticorps SPY, anticorps spdl1, anticorps Spdl1, anticorps spdl1.L, anticorps spdl1.S

Sujet: CCDC99 is required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. CCDC99 is also required for correct spindle orientation. It does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment.
Alias Symbols: FLJ20364, FLJ40690, CCDC99
Protein Interaction Partner: RTP5, PPP1R18, DYX1C1, SPDL1, USP15, TRAF4, CA8, NEK9, SIRT1, HMGCS1, DHX40, YLPM1, SF3B3, ITSN1, UBC, KIAA1377, GPS2,
Protein Size: 605

Poids moléculaire: 67 kDa

ID gène: 54908

NCBI Accession: NM_017785, NP_060255

UniProt: Q96EA4