KDELR2 anticorps (C-Term)

N° du produit ABIN2790796

Détail du produit anti-KDELR2 anticorps

Antigène: KDELR2 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 2 (KDELR2))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDELR2 est non-conjugé

Application: Western Blotting (WB)

Séquence: ASVLQGARTE FLPQQRHKML DTENQKLNSF VADSHQWLCK NAEEKSQKVS

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against KDELR2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human KDELR2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 186 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KDELR2

Antigène: KDELR2 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 2 (KDELR2))

Autre désignation: KDELR2 (KDELR2 Produits)

Synonymes: anticorps kdelr2, anticorps ELP-1, anticorps ERD2.2, anticorps 1110007A14Rik, anticorps kdelr1-a, anticorps KDEL endoplasmic reticulum protein retention receptor 2 L homeolog, anticorps KDEL endoplasmic reticulum protein retention receptor 2, anticorps KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2, anticorps KDEL endoplasmic reticulum protein retention receptor 1 L homeolog, anticorps kdelr2.L, anticorps KDELR2, anticorps Kdelr2, anticorps kdelr1.L

Sujet: Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR2 was the second member of the family to be identified, and it encodes a protein which is 83 % identical to the KDELR1 gene product.
Alias Symbols: ELP-1, ERD2.2, FLJ45532
Protein Interaction Partner: UBC, ELAVL1, SERINC3,
Protein Size: 186

Poids moléculaire: 21 kDa

ID gène: 11014

NCBI Accession: NM_001100603, NP_001094073

Pathways: Maintenance of Protein Location