YTHDF2 anticorps (C-Term)

N° du produit ABIN2790892

Détail du produit anti-YTHDF2 anticorps

Antigène: YTHDF2 (YTH Domain Family, Member 2 (YTHDF2))

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Lapin, Boeuf (Vache), Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp YTHDF2 est non-conjugé

Application: Western Blotting (WB)

Séquence: QEVPLEKAKQ VLKIIASYKH TTSIFDDFSH YEKRQEEEES VKKERQGRGK

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against YTHDF2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human YTHDF2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 579 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur YTHDF2

Antigène: YTHDF2 (YTH Domain Family, Member 2 (YTHDF2))

Autre désignation: YTHDF2 (YTHDF2 Produits)

Synonymes: anticorps MGC82537, anticorps HGRG8, anticorps NY-REN-2, anticorps YTH N(6)-methyladenosine RNA binding protein 2 L homeolog, anticorps YTH N6-methyladenosine RNA binding protein 2, anticorps ythdf2.L, anticorps YTHDF2

Sujet: This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosme 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene.
Alias Symbols: HGRG8, NY-REN-2
Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, RNF2, BMI1, EIF3H, EIF3A, FBXO6, TARDBP, HIPK4, VCAM1, FN1, EPAS1, ESR1, APP, SMAD3, CAND1, CUL3, ELAVL1, POT1, MEPCE, HNRNPH1, HNRNPA1,
Protein Size: 579

Poids moléculaire: 62 kDa

ID gène: 51441

NCBI Accession: NM_016258, NP_057342

UniProt: Q9Y5A9