TTI2 anticorps (N-Term)

N° du produit ABIN2790934

Détail du produit anti-TTI2 anticorps

Antigène: TTI2 (TELO2 Interacting Protein 2 (TTI2))

Épitope: N-Term

Reactivité: Humain, Boeuf (Vache), Chien, Cobaye, Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TTI2 est non-conjugé

Application: Western Blotting (WB)

Séquence: THSLEQPWTT PRSREVAREV LTSLLQVTEC GSVAGFLHGE NEDEKGRLSV

Homologie: Cow: 100%, Dog: 92%, Guinea Pig: 75%, Horse: 100%, Human: 100%, Pig: 92%, Rabbit: 75%

Attributs du produit: This is a rabbit polyclonal antibody against TTI2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TTI2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 508 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TTI2

Antigène: TTI2 (TELO2 Interacting Protein 2 (TTI2))

Autre désignation: TTI2 (TTI2 Produits)

Synonymes: anticorps C8orf41, anticorps TELO2 interacting protein 2, anticorps TTI2, anticorps Tti2

Sujet: TTI2 is a regulator of the DNA damage response (DDR). 'TTI2 is part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). 'TTI2, together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs.
Alias Symbols: C8orf41
Protein Interaction Partner: FUS, UBC, SUMO1, NEDD8, EGFR, ELAVL1, RPAP3, PIH1D1, RUVBL2, TELO2, TTI1, RUVBL1, PRKDC, HSP90AA1, HSPA4,
Protein Size: 508

Poids moléculaire: 56 kDa

ID gène: 80185

NCBI Accession: NM_025115, NP_079391

UniProt: Q6NXR4