DENND1C anticorps (C-Term)

N° du produit ABIN2790995

Cet anticorps Lapin Polyclonal détecte spécifiquement DENND1C dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour DENND1C anticorps (C-Term) (ABIN2790995)

Antigène: DENND1C (DENN/MADD Domain Containing 1C (DENND1C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DENND1C est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DENND1C anticorps

Épitope: C-Term

Fonction: DENND1C Antibody - C-terminal region

Séquence: PSSLEDPRAR PPKALLAERA HLQPREEPGA LNSPATPTSN CQKSQPSSRP

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against DENND1C. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DENND1C

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP68265-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur DENND1C

Antigène: DENND1C (DENN/MADD Domain Containing 1C (DENND1C))

Autre désignation: DENND1C

Sujet:

Background Information: Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1C, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 and bind to clathrin and clathrin adaptor protein-2. Thus, connecdenns link RAB35 activation with the clathrin machinery.

Alternative Symbols: FAM31C

Protein Name: DENN domain-containing protein 1C

Poids moléculaire: 87kDa

ID gène: 79958

NCBI Accession: NP_079174

UniProt: Q8IV53