C1orf86 anticorps (C-Term)

N° du produit ABIN2791345

Détail du produit anti-C1orf86 anticorps

Antigène: C1orf86 (C1ORF86) (Chromosome 1 Open Reading Frame 86 (C1ORF86))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C1orf86 est non-conjugé

Application: Western Blotting (WB)

Séquence: ARSLPQRPAP DPCRAPRVEQ QPSVEGAAAL RSCPMCQKEF APRLTQLDVD

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against C1orf86. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human C1orf86

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 180 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur C1orf86

Antigène: C1orf86 (C1ORF86) (Chromosome 1 Open Reading Frame 86 (C1ORF86))

Autre désignation: C1orf86 (C1ORF86 Produits)

Synonymes: anticorps FAAP20, anticorps FP7162, anticorps Fanconi anemia core complex associated protein 20, anticorps FAAP20

Sujet: C1orf86 is a component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. It promotes translesion synthesis via interaction with REV1.
Alias Symbols: FP7162
Protein Interaction Partner: FANCL, FANCA, UBC, FANCC, APITD1, C19orf40, C17orf70, FANCM, REV1, FANCG, FANCF, FANCB, FANCE, ELAVL1,
Protein Size: 180

Poids moléculaire: 19 kDa

ID gène: 199990

NCBI Accession: NM_182533, NP_872339

UniProt: Q6NZ36