MVB12B anticorps (C-Term)

N° du produit ABIN2791520

Détail du produit anti-MVB12B anticorps

Antigène: MVB12B (Multivesicular Body Subunit 12B (MVB12B))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MVB12B est non-conjugé

Application: Western Blotting (WB)

Séquence: HISLTLPATF RGRNSTRTDY EYQHSNLYAI SAMDGVPFMI SEKFSCVPES

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 85%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MVB12B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MVB12B

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MVB12B

Antigène: MVB12B (Multivesicular Body Subunit 12B (MVB12B))

Autre désignation: MVB12B (MVB12B Produits)

Synonymes: anticorps C9orf28, anticorps FAM125B, anticorps 2610200O14Rik, anticorps 2610528K11Rik, anticorps AI414895, anticorps Fam125b, anticorps RGD1309709, anticorps fam125b, anticorps mvb12b, anticorps fam125ba, anticorps zgc:152929, anticorps multivesicular body subunit 12B, anticorps multivesicular body subunit 12B S homeolog, anticorps multivesicular body subunit 12Ba, anticorps MVB12B, anticorps Mvb12b, anticorps mvb12b.S, anticorps mvb12ba

Sujet: The protein encoded by this gene is a component of the ESCRT-I complex, a heterotetramer, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle. ESCRT-I complex plays an essential role in HIV budding and endosomal protein sorting. Depletion and overexpression of this and related protein (MVB12A) inhibit HIV-1 infectivity and induce unusual viral assembly defects, indicating a role for MVB12 subunits in regulating ESCRT-mediated virus budding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: C9orf28, MVB12B
Protein Interaction Partner: LNX1, gag, UBC, VPS37A, MVB12A, TSG101,
Protein Size: 319

Poids moléculaire: 35 kDa

ID gène: 89853

NCBI Accession: NM_033446, NP_258257

UniProt: Q9H7P6