HIST1H2AE anticorps (N-Term)

N° du produit ABIN2791579

Cet anticorps Lapin Polyclonal détecte spécifiquement HIST1H2AE dans WB. Il présente une réactivité envers Humain, Boeuf (Vache), Rat, Souris, Lapin, Cobaye, Poisson zèbre (Danio rerio), Cheval et Chien.

Aperçu rapide pour HIST1H2AE anticorps (N-Term) (ABIN2791579)

Antigène: HIST1H2AE (Histone Cluster 1, H2ae (HIST1H2AE))

Reactivité: Humain, Boeuf (Vache), Rat, Souris, Lapin, Cobaye, Poisson zèbre (Danio rerio), Cheval, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HIST1H2AE est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HIST1H2AE anticorps

Épitope: N-Term

Séquence: GKQGGKARAK AKTRSSRAGL QFPVGRVHRL LRKGNYSERV GAGAPVYLAA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against HIST1H2AE. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human HIST1H2AE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HIST1H2AE

Antigène: HIST1H2AE (Histone Cluster 1, H2ae (HIST1H2AE))

Autre désignation: HIST1H2AE

Sujet: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Alias Symbols: H2A.1, H2A.2, H2A/a, H2AFA
Protein Interaction Partner: UBC, HUWE1, SUZ12, EZH2, ITGA4, CAND1, COPS5, CUL1, CUL4A, CUL4B, CUL5, NFX1, NEDD8, TONSL, SUMO1, EID1, UHRF1, NAP1L4,
Protein Size: 130

Poids moléculaire: 14 kDa

ID gène: 3012

NCBI Accession: NM_021052, NP_066390

UniProt: P04908

Pathways: Telomere Maintenance