PREX2 anticorps (N-Term)

N° du produit ABIN2791874

Cet anticorps Lapin Polyclonal détecte spécifiquement PREX2 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour PREX2 anticorps (N-Term) (ABIN2791874)

Antigène: PREX2 (DEPDC2) (DEP Domain Containing 2 (DEPDC2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PREX2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PREX2 anticorps

Épitope: N-Term

Séquence: ERDYVGTLEF LVSAFLHRMN QCAASKVDKN VTEETVKMLF SNIEDILAVH

Homologie: Cow: 93%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against PREX2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PREX2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PREX2

Antigène: PREX2 (DEPDC2) (DEP Domain Containing 2 (DEPDC2))

Autre désignation: PREX2

Sujet: PREX2 functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. PREX2 mediates the activation of RAC1 in a PI3K-dependent manner. PREX2 may be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.
Protein Interaction Partner: PPP1CA, MTOR, TGFBR1,
Protein Size: 1606

Poids moléculaire: 182 kDa

ID gène: 80243

UniProt: Q70Z35