PREX2 anticorps (N-Term)
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- Antigène Voir toutes PREX2 (DEPDC2) Anticorps
- PREX2 (DEPDC2) (DEP Domain Containing 2 (DEPDC2))
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Épitope
- N-Term
- Reactivité
- Humain, Souris, Rat, Porc, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PREX2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- ERDYVGTLEF LVSAFLHRMN QCAASKVDKN VTEETVKMLF SNIEDILAVH
- Homologie
- Cow: 93%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against PREX2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human PREX2
- Top Product
- Discover our top product DEPDC2 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PREX2 (DEPDC2) (DEP Domain Containing 2 (DEPDC2))
- Autre désignation
- PREX2 (DEPDC2 Produits)
- Synonymes
- anticorps 6230420N16Rik, anticorps DEP.2, anticorps DEPDC2, anticorps P-REX2, anticorps AI316880, anticorps AI553603, anticorps C030045D06Rik, anticorps D430013K02, anticorps Depdc2, anticorps P-Rex2, anticorps phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2, anticorps phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2, anticorps PREX2, anticorps Prex2
- Sujet
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PREX2 functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. PREX2 mediates the activation of RAC1 in a PI3K-dependent manner. PREX2 may be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.
Protein Interaction Partner: PPP1CA, MTOR, TGFBR1,
Protein Size: 1606 - Poids moléculaire
- 182 kDa
- ID gène
- 80243
- UniProt
- Q70Z35
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