TXN anticorps (C-Term)
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- Antigène Voir toutes TXN Anticorps
- TXN (Thioredoxin (TXN))
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Épitope
- C-Term
- Reactivité
- Humain, Rat, Souris, Boeuf (Vache), Porc, Lapin, Chien, Cobaye, Cheval, Mouton
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TXN est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- NVIFLEVDVD DCQDVASECE VKCMPTFQFF KKGQKVGEFS GANKEKLEAT
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against TXN. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human TXN
- Top Product
- Discover our top product TXN Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- TXN (Thioredoxin (TXN))
- Autre désignation
- TXN (TXN Produits)
- Synonymes
- anticorps TRDX, anticorps TRX, anticorps TRX1, anticorps ADF, anticorps AW550880, anticorps Trx1, anticorps Txn, anticorps trx, anticorps TXN, anticorps SCM1.18, anticorps trxA3, anticorps thioredoxin, anticorps TR-1, anticorps Trx-1, anticorps thioredoxin, anticorps thioredoxin 1, anticorps thioredoxin L homeolog, anticorps similar to 44RRORF109c hypothetical protein; similar to bacterial thioredoxin (SwissProt P06544), anticorps thioredoxin pseudogene, anticorps cytosolic thioredoxin Trx1, anticorps TXN, anticorps Txn1, anticorps txn.L, anticorps txn, anticorps trx, anticorps SCO0885, anticorps PHG25ORF099c, anticorps LOC100349046, anticorps Txn, anticorps trx1
- Sujet
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TXN participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. It plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. It nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. It induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.
ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55)
Alias Symbols: TRDX, TRX, TRX1
Protein Interaction Partner: NR3C1, GPX1, APEX1, SRP9, PARK2, TXNIP, UBD, Melk, NPM1, PAN2, UBL4A, UBC, DYNLT1, SIAH1, NFE2, MYD88, MYC, MLH1, IFIT3, CDKN1A, ACTN4, GPRASP2, HCVgp1, PRDX1, MAP3K5, SFXN1, UBL5, UBQLN4, TAX1BP3, AHCYL1, SSSCA1, SYNCRIP, WDR1, ATP6V1F, UBE2V1, UBE2D2, S
Protein Size: 105 - Poids moléculaire
- 11 kDa
- ID gène
- 7295
- NCBI Accession
- NM_003329, NP_003320
- UniProt
- P10599
- Pathways
- Carbohydrate Homeostasis, Cell RedoxHomeostasis
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