Sorbs2 anticorps (Middle Region)

N° du produit ABIN2792074

Détail du produit anti-Sorbs2 anticorps

Antigène: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Sorbs2 est non-conjugé

Application: Western Blotting (WB)

Séquence: LRPRDRSSTE KHDWDPPDRK VDTRKFRSEP RSIFEYEPGK SSILQHERPA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 86%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SORBS2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human SORBS2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Sorbs2

Antigène: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Autre désignation: SORBS2 (Sorbs2 Produits)

Synonymes: anticorps Argbp2, anticorps 2010203O03Rik, anticorps 9430041O17Rik, anticorps A530071H08, anticorps mKIAA0777, anticorps argbp2, anticorps pro0618, anticorps 9430041O17RIK, anticorps DKFZp468F1119, anticorps ARGBP2, anticorps PRO0618, anticorps sorbin and SH3 domain containing 2, anticorps Sorbs2, anticorps SORBS2, anticorps sorbs2

Sujet: SORBS2 is an adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. It can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1.
Alias Symbols: ARGBP2, PRO0618
Protein Interaction Partner: ATPAF2, SH2D4A, VPS37C, EFS, SORBS2, NCK2, YWHAE, WAS, SUZ12, YWHAB, BAG3, HCVgp1, YWHAZ, MDM2, AKT2, nef, WASF1, ADAM15, PTPN12, ABL1, ACTN1, PALLD, SEMA6A, NR1H2, EGFR, DLGAP4, DLGAP1, DLGAP2, SYNJ1, FLOT1, PAK2, RPL9, PAK1, TRAF4, PTK2B, VCL, PKM, CBL,
Protein Size: 644

Poids moléculaire: 70 kDa

ID gène: 8470

NCBI Accession: NM_001145670, NP_001139142