Sorbs2 anticorps (Middle Region)
Aperçu rapide pour Sorbs2 anticorps (Middle Region) (ABIN2792074)
Antigène
Voir toutes Sorbs2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- LRPRDRSSTE KHDWDPPDRK VDTRKFRSEP RSIFEYEPGK SSILQHERPA
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 86%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against SORBS2. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of Human SORBS2
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))
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Autre désignation
- SORBS2
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Sujet
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SORBS2 is an adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. It can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1.
Alias Symbols: ARGBP2, PRO0618
Protein Interaction Partner: ATPAF2, SH2D4A, VPS37C, EFS, SORBS2, NCK2, YWHAE, WAS, SUZ12, YWHAB, BAG3, HCVgp1, YWHAZ, MDM2, AKT2, nef, WASF1, ADAM15, PTPN12, ABL1, ACTN1, PALLD, SEMA6A, NR1H2, EGFR, DLGAP4, DLGAP1, DLGAP2, SYNJ1, FLOT1, PAK2, RPL9, PAK1, TRAF4, PTK2B, VCL, PKM, CBL,
Protein Size: 644 -
Poids moléculaire
- 70 kDa
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ID gène
- 8470
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NCBI Accession
- NM_001145670, NP_001139142
Antigène
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